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Olokizumab

(Synonyms: CDP 6038; OKZ)
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Based on 1 publication(s) in Google Scholar

Olokizumab (CDP 6038) is a humanized monoclonal antibody that targets interleukin-6 (IL-6). Olokizumab inhibits IL-6-induced STAT-3 phosphorylation. Olokizumab is used in the study of arthritis.

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  • Pureté: 99.54%
  • CAS No.: 1007223-17-7
  • Masse moléculaire:145.94 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Olokizumab
  • Experimental Validation Results for Olokizumab
  • Experimental Validation Results for Olokizumab
  • Olokizumab Chemical Structure
    Olokizumab Chemical Structure
CAS No.: 1007223-17-7
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Olokizumab Product Recommendations:

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609-228-6898
[email protected] [email protected]
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Flow cytometric analysis of 1.5×106 Siha cells with Olokizumab (HY-P99210, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Immobilized Human IL-6/IFNb2, His Tag can bind Olokizumab. The EC50 for this effect is 9.558 ng/mL.

  • Olokizumab Chemical Structure
    1/16
  • Olokizumab
  • Flow cytometric analysis of 1.5×106 Siha cells with Olokizumab (HY-P99210, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Immobilized Human IL-6/IFNb2, His Tag can bind Olokizumab. The EC50 for this effect is 9.558 ng/mL.