PF-1010
PF-1010 is a CD73 inhibitor with an IC50 ranging from 101 to 1000 nM. PF-1010 blocks the interaction between CD73 protein and its substrate, and inhibits the enzymatic activity of CD73. PF-1010 is applicable to the research of cancer, infectious diseases, autoimmune diseases and neurodegenerative diseases.
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- CAS No.: 2653350-02-6
- Formule: C34H27ClF3N3O6
- Masse moléculaire:666.04
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Chemical Information
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CAS No. 2653350-02-6
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Masse moléculaire 666.04
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Formule C34H27ClF3N3O6
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SMILES
N#CC(C=C1)=CC=C1COC(C=C(C(Cl)=C2)NCC3=C(C(C4=CC=C(C=C4)OC(F)(F)F)=CC=C3)C)=C2CN5[C@H](COC5=O)C(O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)