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Cat. No.: HY-190191

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QC-65

QC-65 is a HO-1/HO-2 inhibitor with IC₅₀ = 4.0 μM for HO-1 and IC₅₀ = 11.3 μM for HO-2. QC-65 can be used in research on HO-1-mediated related diseases, such as cancer.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 741628-94-4
Formule: C₁₃H₁₄N₂O
Masse moléculaire:214.26

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

QC-65 Chemical Structure

CAS No.: 741628-94-4

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
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Description

QC-65 is a HO-1/HO-2 inhibitor with IC₅₀ = 4.0 μM for HO-1 and IC₅₀ = 11.3 μM for HO-2. QC-65 can be used in research on HO-1-mediated related diseases, such as cancer^[1].

IC₅₀ & Target

^[1]

HO-1

4.0 μM (IC₅₀)

HO-2

11.3 μM (IC₅₀)

Voir tous les produits spécifiques à Isoform Heme Oxygenase (HO) :

HO-1
HO-2

In Vitro

QC-65 (1-100 μM; 60 min at 37 °C) inhibits rat spleen HO-1 and rat brain HO-2 with IC₅₀ values of 4.0 μM and 11.3 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 741628-94-4
Masse moléculaire 214.26
Formule C₁₃H₁₄N₂O
SMILES

O=C(CCC1=CC=CC=C1)CN2C=CN=C2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Fallica AN, et al. Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent Antiproliferative Activity. Journal of medicinal chemistry. 2021 Sep 23;64(18):13373-13393. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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QC-65

Voir tous les produits spécifiques à Isoform Heme Oxygenase (HO)

Activité biologique

Description

IC50 & Target

In Vitro

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

QC-65 Related Classifications

HY-190191 Related Classifications

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