Saintopin
Saintopin is an antitumor antibiotic. Saintopin is also an inhibitor of DNA topoisomerases I and II. Saintopin induces DNA cleavage.
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- CAS No.: 131190-63-1
- Formule: C18H10O7
- Masse moléculaire:338.27
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Topoisomerase I |
Topoisomerase II |
Chemical Information
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CAS No. 131190-63-1
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Masse moléculaire 338.27
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Formule C18H10O7
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SMILES
O=C(C1=CC(O)=CC(O)=C1C2=O)C3=C2C(O)=C4C(O)=CC(O)=CC4=C3
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Synonyms
UCT-1003
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Yamashita Y, et al. Saintopin, a new antitumor antibiotic with topoisomerase II dependent DNA cleavage activity, from Paecilomyces. J Antibiot (Tokyo). 1990 Oct;43(10):1344-6. [Content Brief]
[2]. eteurtre F, et al. Saintopin, a dual inhibitor of DNA topoisomerases I and II, as a probe for drug-enzyme interactions. J Biol Chem. 1994 Nov 18;269(46):28702-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)