VY7523
VY7523 is a monoclonal antibody and a selective inhibitor of pathological Tau. VY7523 reduces the propagation of pathogenic Tau in transgenic mouse models. VY7523 can be used in the research of Alzheimer's disease. The isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Isotype
Human IgG4 kappa
Recommend Isotype Controls
Species Reactivity
Human
In Vitro
VY7523 exhibits over 200-fold higher selectivity for pathological tau than for recombinant wild-type h-tau[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Gene ID
Accession
Target
Tau
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Application
ELISA, FACS, Functional assay
Chemical Information
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VY7523 Related Classifications
HY-P992484 Related Classifications
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Keywords
- VY7523
- VY 7523
- VY-7523
- Tau Protein
- healthy volunteers
- human wild-type tau
- pathogenic tau propagation
- early Alzheimer’s disease patients
- C-terminal domain of pathologic tau
- pathologic tau (C-terminal domain)
- transgenic mouse models
- recombinant human wild-type tau
- Alzheimer's disease
- P301S transgenic mice
- Inhibitor
- inhibitor
- inhibit