Chemerin-9, mouse
Chemerin-9, mouse (Chemerin148-156, mouse) is a C-terminal nonapeptide of chemerin. Chemerin-9, mouse is a ligand for ChemR23 (EC50 = 42 nM). Chemerin-9, mouse reduces basal lipolysis in primary mouse white adipocytes(IC50 = 3.3 nM). Chemerin-9, mouse enhances memory and relieves Aβ1-42-induced memory impairment in AD mice. Chemerin-9, mouse also inhibits atherogenesis.
For research use only. We do not sell to patients.
- CAS No.: 686324-96-9
- Formula: C51H68N10O12
- Molecular Weight:1013.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
All Chemerin Receptor Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 686324-96-9
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Molecular Weight 1013.15
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Formula C51H68N10O12
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Synonyms
Chemerin148–156, mouse
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Sequence
Phe-Leu-Pro-Gly-Gln-Phe-Ala-Phe-Ser
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Sequence Shortening
FLPGQFAFS
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Large-size fat particle sorting
Large-size fat particle sorting is widely used to isolate cells up to 200 μm in diameter. Single-cell flow sorting will allow greater insight into adipocyte heterogeneity by identifying gene expression, protein composition, and metabolic signatures at the single-cell level.
Purity & Documentation
References
[1]. Shimamura K, et al. Identification of a stable chemerin analog with potent activity toward ChemR23. Peptides. 2009 Aug;30(8):1529-38. [Content Brief]
[2]. Sato K, et al. Chemerin-9, a potent agonist of chemerin receptor (ChemR23), prevents atherogenesis. Clin Sci (Lond). 2019 Aug 20;133(16):1779-1796. [Content Brief]
[3]. Lei Z, et al. Chemerin-9 Peptide Enhances Memory and Ameliorates Aβ1-42-Induced Object Memory Impairment in Mice. Biol Pharm Bull. 2020 Feb 1;43(2):272-283. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chemerin-9, mouse Related Classifications
HY-P2712 Related Classifications
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