Chenodeoxycholic acid 3-sulfate-d₄ disodium

Cat. No.: HY-141918S Purity: 99%: Data Sheet
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SDS
Handling Instructions
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Chenodeoxycholic acid 3-sulfate-d₄ disodium is the deuterium labeled Chenodeoxycholic acid 3-sulfate.

For research use only. We do not sell to patients.

Chenodeoxycholic acid 3-sulfate-d<sub>4</sub> disodium

Chenodeoxycholic acid 3-sulfate-d₄ disodium Chemical Structure

Size	Stock	Quantity
500 μg	Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	Get quote
10 mg	Get quote

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Other Forms of Chenodeoxycholic acid 3-sulfate-d₄ disodium:

Chenodeoxycholic acid 3-sulfate disodium In-stock

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Biological Activity
Purity & Documentation
References
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Description

Chenodeoxycholic acid 3-sulfate-d₄ disodium is the deuterium labeled Chenodeoxycholic acid 3-sulfate^[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

520.62

Formula

C₂₄H₃₄D₄Na₂O₇S

Unlabeled CAS

60237-34-5

Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])(C[C@]1([C@@]([H])(C2([2H])[2H])C[C@H]([C@@]3([C@@]1(CC[C@]4([C@]3(CC[C@@]4([C@@H](CCC(O[Na])=O)C)[H])[H])C)[H])[H])O)C)[C@H]2OS(=O)(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (96.04 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9208 mL	9.6039 mL	19.2079 mL
5 mM	0.3842 mL	1.9208 mL	3.8416 mL
10 mM	0.1921 mL	0.9604 mL	1.9208 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

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Concentration _(final)

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In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (250 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.9208 mL	9.6039 mL	19.2079 mL	48.0197 mL
	5 mM	0.3842 mL	1.9208 mL	3.8416 mL	9.6039 mL
	10 mM	0.1921 mL	0.9604 mL	1.9208 mL	4.8020 mL
	15 mM	0.1281 mL	0.6403 mL	1.2805 mL	3.2013 mL
	20 mM	0.0960 mL	0.4802 mL	0.9604 mL	2.4010 mL
	25 mM	0.0768 mL	0.3842 mL	0.7683 mL	1.9208 mL
	30 mM	0.0640 mL	0.3201 mL	0.6403 mL	1.6007 mL
	40 mM	0.0480 mL	0.2401 mL	0.4802 mL	1.2005 mL
	50 mM	0.0384 mL	0.1921 mL	0.3842 mL	0.9604 mL
	60 mM	0.0320 mL	0.1601 mL	0.3201 mL	0.8003 mL
	80 mM	0.0240 mL	0.1200 mL	0.2401 mL	0.6002 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.