Chlamydia pneumoniae-IN-1

製品番号: HY-153626: Data Sheet 取扱説明書
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Chlamydia pneumoniae-IN-1 (compound 55), a benzimidazole, shows high activity against the bacterium. Chlamydia pneumoniae-IN-1 has 99% inhibition of C. pneumoniae Growth at 10 μM, and has 95% inhibition effect on the viability of the host cells at 10 μM. Chlamydia pneumoniae-IN-1 inhibits the growth of the CV-6 strain with a MIC of 12.6 μM. Chlamydia pneumoniae-IN-1 has antichlamydial efficiency.

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Chlamydia pneumoniae-IN-1 構造式

CAS 番号 : 518010-44-1

容量	価格（税別）	在庫状況	数量
1 mg	$545	お問い合わせ 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
5 mg	$1353	お問い合わせ 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	$1961	お問い合わせ 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
NIH3T3	IC₅₀	16.7 μM Compound: 22	Cytotoxicity against mouse NIH/3T3 cells assessed as viability after 48 hrs by alamarBlue assay Cytotoxicity against mouse NIH/3T3 cells assessed as viability after 48 hrs by alamarBlue assay	[PMID: 25827525]
THP-1	IC₅₀	10.5 μM Compound: 22	Antileishmanial activity against Leishmania donovani MHOM/SD/1962/1S-Cl2d infected THP1 cells assessed as inhibition of intracellular axenic amastigote after 48 hrs at 50 uM by Bright-Glo luciferase assay Antileishmanial activity against Leishmania donovani MHOM/SD/1962/1S-Cl2d infected THP1 cells assessed as inhibition of intracellular axenic amastigote after 48 hrs at 50 uM by Bright-Glo luciferase assay	[PMID: 25827525]

分子量

333.41

分子式

C₁₉H₁₅N₃OS

CAS 番号

518010-44-1

SMILES

O=C(C1=CC=CS1)NC2=CC=CC(C3=NC4=CC=C(C)C=C4N3)=C2

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Leena Keurulainen, et al. Design and synthesis of 2-arylbenzimidazoles and evaluation of their inhibitory effect against Chlamydia pneumonia. J Med Chem. 2010 Nov 11;53(21):7664-74. [Content Brief]