CRBN ligand-395
Based on 1 Customer Validation
CRBN ligand-395 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-395 can be linked to a target protein ligand via a linker to form a PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 2641512-74-3
- Formula: C16H21ClN2O2
- Molecular Weight:308.81
-
Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
Biological Activity
|
Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2641512-74-3
-
Appearance Solid
-
Molecular Weight 308.81
-
Formula C16H21ClN2O2
-
Color White to off-white
-
SMILES
Cl.O=C1NC(=O)C(C2=CC=C(C=C2)C3CCNCC3)CC1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Purity & Documentation
-
Data Sheet (241 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)