CVNTANST
CVNTANST is a fluorescent peptide that targets vimentin. CVNTANST binds to vimentin and restricts the ethylene bond rotation of tetraphenylethylene, triggering fluorescence turn-on via the restriction of intramolecular motion mechanism. CVNTANST enables wash-free fluorescence detection and imaging of vimentin-positive epithelial-mesenchymal transition (EMT)-type cancer cells and tumor tissues. CVNTANST can be used for research on EMT-type cancers.
For research use only. We do not sell to patients.
- CAS No.: 2559743-70-1
- Formula: C30H52N10O14S
- Molecular Weight:808.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
CVNTANST peptide couples to both Z and E isomers of the TPE-bis-maleimide precursor via thiol-maleimide click chemistry, producing the corresponding vimentin-targeting AIEgen-peptide conjugates Vim-TPE-1 and Vim-TPE-2[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2559743-70-1
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Molecular Weight 808.86
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Formula C30H52N10O14S
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SMILES
O=C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CS)N
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Sequence
Cys-Val-Asn-Thr-Ala-Asn-Ser-Thr
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Sequence Shortening
CVNTANST
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CVNTANST Related Classifications
HY-P12218 Related Classifications
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