1,16-Hexadecanediol
Based on 1 Customer Validation
1,16-Hexadecanediol (Hexadecamethylene glycol) is a diol compound derived from plant wax and an inducer of appressorium formation in Magnaporthe grisea. Its activities include reversing PepEST-mediated inhibition and promoting the accumulation of α-1,3-glucan (a-1,3-glucan) on germ tubes and appressoria. 1,16-Hexadecanediol activates the Mps1 MAP kinase pathway through Mps1p phosphorylation. 1,16-Hexadecanediol can be used for research on rice blast and anthracnose.
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- Reinheit : 99.93%
- CAS. Nr.: 7735-42-4
- Formel: C16H34O2
- Molecular Weight:258.44
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Speicherung:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biologische Aktivität
Beschreibung
In Vitro
1,16-Hexadecanediol (0.01 mM; 24 h) strongly reverses PepEST-mediated inhibition of appressorium formation in M. grisea 70-15, restoring the formation rate to 93.7%[1].
1,16-Hexadecanediol (50 mM; 16-24 h) induces the accumulation of α-1,3-glucan on appressoria and germ tubes of M. grisea developed on coverslips and increases the tolerance of germ tube cell walls to chitinase digestion[2].
1,16-Hexadecanediol (50 mM; 20-40 min) activates the Mps1 MAP kinase pathway by inducing phosphorylation of Mps1p in M. grisea[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 7735-42-4
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Appearance Solid
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Molecular Weight 258.44
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Formel C16H34O2
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Color White to off-white
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SMILES
C(CCCCCCCCO)CCCCCCCO
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Synonyms
Hexadecamethylene glycol
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 10 mg/mL (38.69 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8694 mL | 19.3469 mL | 38.6937 mL | 96.7343 mL |
| 5 mM | 0.7739 mL | 3.8694 mL | 7.7387 mL | 19.3469 mL | |
| 10 mM | 0.3869 mL | 1.9347 mL | 3.8694 mL | 9.6734 mL | |
| 15 mM | 0.2580 mL | 1.2898 mL | 2.5796 mL | 6.4490 mL | |
| 20 mM | 0.1935 mL | 0.9673 mL | 1.9347 mL | 4.8367 mL | |
| 25 mM | 0.1548 mL | 0.7739 mL | 1.5477 mL | 3.8694 mL | |
| 30 mM | 0.1290 mL | 0.6449 mL | 1.2898 mL | 3.2245 mL |