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Art. -Nr.: HY-N3647

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Cudraxanthone D

Cudraxanthone D is a Xanthones product that can be isolated from the roots of Cudrania tricuspidata.

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CAS. Nr.: 96552-41-9
Formel: C₂₄H₂₆O₆
Molecular Weight:410.46

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (243 KB)

Cudraxanthone D Chemical Structure

CAS. Nr.: 96552-41-9

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Biologische Aktivität

Beschreibung

Cudraxanthone D is a Xanthones product that can be isolated from the roots of Cudrania tricuspidata^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
BTI-TN-5B1-4	IC₅₀	57.6 μM Compound: 3	Inhibition of human ACAT1 expressed in Hi5 cells Inhibition of human ACAT1 expressed in Hi5 cells	[PMID: 16919944]
BTI-TN-5B1-4	IC₅₀	75.2 μM Compound: 3	Inhibition of human ACAT2 expressed in Hi5 cells Inhibition of human ACAT2 expressed in Hi5 cells	[PMID: 16919944]
RAW264.7	IC₅₀	16.1 μM Compound: 23	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess method Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess method	[PMID: 26073007]
SH-SY5Y	EC₅₀	>50 μM Compound: Cudraxanthone D	Neuroprotective activity in human SH-SY5Y cells assessed as reduction in 1-methyl-4-phenylpyridinium ion-induced cell death after 48 hrs by MTT assay Neuroprotective activity in human SH-SY5Y cells assessed as reduction in 1-methyl-4-phenylpyridinium ion-induced cell death after 48 hrs by MTT assay	[PMID: 27420919]
SH-SY5Y	EC₅₀	4.8 μM Compound: Cudraxanthone D	Neuroprotective activity in human SH-SY5Y cells assessed as reduction in oxygen glucose deprivation-induced cell death incubated for 16 hrs under hypoxic condition followed by incubation for 24 hrs under normoxic condition by MTT assay Neuroprotective activity in human SH-SY5Y cells assessed as reduction in oxygen glucose deprivation-induced cell death incubated for 16 hrs under hypoxic condition followed by incubation for 24 hrs under normoxic condition by MTT assay	[PMID: 27420919]

Chemical Information

CAS. Nr. 96552-41-9
Molecular Weight 410.46
Formel C₂₄H₂₆O₆
SMILES

O=C1C2=C(OC3=C1C(O)=CC(OC)=C3C(C)(C)C=C)C=C(O)C(O)=C2C/C=C(C)\C
Structure Classification
- Phenols
- Xanthones
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.