NKG2A/CD159a
NKG2A (CD159a), encoded by KLRC1, is an inhibitory C-type lectin receptor that forms obligate heterodimers with CD94 on NK cells and CD8 T cells. The CD94/NKG2A complex recognizes the non-classical MHC class I molecule HLA-E presenting signal peptides derived from classical HLA leaders, and the cytoplasmic ITIM of NKG2A delivers inhibitory signals via SHP phosphatases, protecting healthy HLA-E-expressing cells from NK attack. Elevated NKG2A expression on tumor-infiltrating NK and CD8 T cells is associated with impaired antitumor immunity, and the blocking antibody monalizumab is in clinical development, including combinations with EGFR-directed therapy in head and neck cancer.
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NKG2A/CD159a Recombinant Proteins (17)
NKG2A Protein, Human (Biotinylated, HEK293, His-Avi)
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Art. -Nr.: HY-P78182
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A Protein, Human (HEK293, His)
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Art. -Nr.: HY-P70551
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A-CD94 Heterodimer Protein, Human (HEK293, His-Flag)
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Art. -Nr.: HY-P70713
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A-CD94 Heterodimer Protein, Human (Biotinylated, HEK293, His-Avi)
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Art. -Nr.: HY-P77806
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A-CD94 Heterodimer Protein, Cynomolgus (HEK293, His-Flag)
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Art. -Nr.: HY-P700796
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A Protein, Mouse (HEK293, His)
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Art. -Nr.: HY-P74690
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A-CD94 Heterodimer Protein, Mouse (HEK293, mFc)
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Art. -Nr.: HY-P77808
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A Protein, Cynomolgus/Rhesus macaque (HEK293, His)
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Art. -Nr.: HY-P78576
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc)
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Art. -Nr.: HY-P77105
Reinheit: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A Protein, Human (HEK293, His-Avi)
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Art. -Nr.: HY-P78499
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A-CD94 Heterodimer Protein, Human (HEK293, Fc-Flag)
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Art. -Nr.: HY-P77803
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A-CD94 Heterodimer Protein, Human (HEK293, mFc)
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Art. -Nr.: HY-P77804
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A-CD94 Heterodimer Protein, Human (HEK293, His-Avi)
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Art. -Nr.: HY-P77805
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A Protein, Human (HEK293, Fc)
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Art. -Nr.: HY-P78497
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A Protein, Human (Biotinylated, HEK293, His)
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Art. -Nr.: HY-P74691
Reinheit: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A-CD94 Heterodimer Protein, Mouse (HEK293, His)
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Art. -Nr.: HY-P704966
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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NKG2A-CD94 Heterodimer Protein, Mouse (HEK293, Fc)
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Art. -Nr.: HY-P704962
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KLRC1; NKG2-A/B-Activating NK Receptor; Prev. NKG2; NKG2-B; NKG2-A; NKG2A; CD159a; NKG2-A/B Type II Integral Membrane Protein; Killer Cell Lectin-Like Receptor Subfamily C, Member 1; Natural Killer Group Protein 2; NKG2-A/NKG2-B Type II Integral Membrane
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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Capetin (28-54), human
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Synonyms: Serpin B6; Cytoplasmic Antiproteinase; cap; Peptidase Inhibitor
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
