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Cat. No.: HY-P11100

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PepW

PepW is a potent antimicrobial peptide targeting the capsule of multidrug-resistant Klebsiella pneumoniae (MIC=2-8 μM). PepW achieves bactericidal activity via capsule polysaccharide aggregation and structural disruption. PepW is promising for research of infectious diseases caused by Gram-negative bacteria (e.g., pneumonia, sepsis).

For research use only. We do not sell to patients.

Formula: C₁₁₄H₁₅₀N₂₆O₂₁
Molecular Weight:2220.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PepW Chemical Structure

Size

Price

Stock

Quantity

Sample (0.1mg)

In-stock

(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

Molecular Weight 2220.57
Formula C₁₁₄H₁₅₀N₂₆O₂₁
Sequence

Trp-Trp-Trp-Ala-{Dab}-Tyr-Gly-Leu-{Dab}-Leu-Leu-{Dab}-Tyr-{Dab}-{Dab}-Trp-Tyr
Sequence Shortening

WWWA-{Dab}-YGL-{Dab}-LL-{Dab}-Y-{Dab}-{Dab}-WY
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fleeman RM, et al. Defining principles that influence antimicrobial peptide activity against capsulated Klebsiella pneumoniae. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27620-27626. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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