Piridoxilate
Piridoxilate (Piridoxylate), a glyoxylate derivative, is an anti-anoxic agent. Piridoxilate can be used in research on vascular diseases and coronary occlusion.
For research use only. We do not sell to patients.
- CAS No.: 24340-35-0
- Formula: C20H26N2O12
- Molecular Weight:486.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
Piridoxilate (Piridoxylate; 0-20 nM) enhances the synthesis of hippurate from benzoate in rat hepatocytes[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Sprague-Dawley rats with cerebral hypoxia[1]
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Dosage:120 mg/kg
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Administration:Intraperitoneal injection
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Result:Enhanced resistance of these animals to hypoxia.
Chemical Information
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CAS No. 24340-35-0
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Molecular Weight 486.43
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Formula C20H26N2O12
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SMILES
OC(C(OC1=C(C)N=CC(CO)=C1CO)O)=O.OC(C(O)OCC2=CN=C(C)C(O)=C2CO)=O
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Synonyms
Piridoxylate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Millet YA, et, al. Evaluation sur l'électrocorticogramme du rat de l'action protectrice du piridoxilate contre l'hypoxie cérébrale [Evaluation by electrocorticogram of the protective action of piridoxilate against cerebral hypoxia in rats]. C R Seances Soc Biol Fil. 1977;171(2):398-405. [Content Brief]
[2]. Coude FX, et, al. Potentiation by piridoxilate of the synthesis of hippurate from benzoate in isolated rat hepatocytes. An approach to the determination of new pathways of nitrogen excretion in inborn errors of urea synthesis. Clin Chim Acta. 1984 Jan 31;136(2-3):211-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)