1. Neuronal Signaling GPCR/G Protein Metabolic Enzyme/Protease
  2. Cannabinoid Receptor Endogenous Metabolite
  3. Dihomo-γ-Linolenoyl Ethanolamide

Dihomo-γ-Linolenoyl Ethanolamide, an endocannabinoid, is a cannabinoid (CB) receptor agonist with Kis of 857 nM and 598 nM for human recombinant CB1 and CB2 receptors, respectively.

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Dihomo-γ-Linolenoyl Ethanolamide

Dihomo-γ-Linolenoyl Ethanolamide 화학구조

CAS No. : 150314-34-4

사이즈 가격 재고 수량
Solvent
5 mg (71.52 mM * 200 μL in Ethanol) 해외재고보유
Solvent
10 mg (71.52 mM * 400 μL in Ethanol) 해외재고보유

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  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Dihomo-γ-Linolenoyl Ethanolamide, an endocannabinoid, is a cannabinoid (CB) receptor agonist with Kis of 857 nM and 598 nM for human recombinant CB1 and CB2 receptors, respectively[1].

IC50 & Target[1]

hCB1-R

857 nM (Ki)

hCB2-R

598 nM (Ki)

Cellular Effect
Cell Line Type Value Description References
RBL-2H3 IC50
>50 μM
Compound: 13
Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2
Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2
[PMID: 31618024]
분자량

349.55

화학식

C22H39NO2

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(NCCO)=O

Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.

보관

Solution, -20°C, 2 years

순도&문서

Purity: 99.9%

References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Dihomo-γ-Linolenoyl Ethanolamide
Cat. No.:
HY-113070
수량:
MCE Japan Authorized Agent: