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Cat. No.: HY-N10604

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Dihydromaniwamycin E

Dihydromaniwamycin E is a heat-shock metabolite with antiviral activity against influenza and SARS-CoV-2 viruses.

For research use only. We do not sell to patients.

CAS No.: 3033567-35-7
Formula: C₁₀H₂₂N₂O₂
Molecular Weight:202.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Dihydromaniwamycin E Chemical Structure

CAS No.: 3033567-35-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Dihydromaniwamycin E is a heat-shock metabolite with antiviral activity against influenza and SARS-CoV-2 viruses^[1].

IC₅₀ & Target

Influenza, SARS-CoV-2^[1]

In Vitro

Dihydromaniwamycin E shows an inhibitory effect against influenza (H1N1) virus infection in MDCK cells by a plaque assay, exhibiting an IC₅₀ of 25.7 μM^[1].
Dihydromaniwamycin E displays antiviral activity against SARS-CoV-2, the causative agent of COVID-19 infection, in 293TA cells, exhibiting an IC₅₀ of 19.7 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3033567-35-7
Molecular Weight 202.29
Formula C₁₀H₂₂N₂O₂
SMILES

CCCCCC/[N+]([O-])=N/[C@@H]([C@@H](O)C)C
Structure Classification
- Others
Initial Source
- Microorganisms
Streptomyces sp.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Saito S, et al. Dihydromaniwamycin E, a Heat-Shock Metabolite from Thermotolerant Streptomyces sp. JA74, Exhibiting Antiviral Activity against Influenza and SARS-CoV-2 Viruses. J Nat Prod. 2022 Oct 12:acs.jnatprod.2c00550. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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