3-Fluorocatechol
Based on 1 Customer Validation
3-Fluorocatechol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
For research use only. We do not sell to patients.
- Purity: 99.32%
- CAS No.: 363-52-0
- Formula: C6H5FO2
- Molecular Weight:128.10
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | GI50 |
57.55 μM
Compound: 3d
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Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by SRB assay
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[PMID: 28041801] |
| TK-10 | GI50 |
84.68 μM
Compound: 3d
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Cytotoxicity against human TK10 cells assessed as cell growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human TK10 cells assessed as cell growth inhibition after 48 hrs by SRB assay
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[PMID: 28041801] |
| UACC-62 | GI50 |
35.24 μM
Compound: 3d
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Cytotoxicity against human UACC62 cells assessed as cell growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human UACC62 cells assessed as cell growth inhibition after 48 hrs by SRB assay
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[PMID: 28041801] |
Chemical Information
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CAS No. 363-52-0
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Appearance Solid
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Molecular Weight 128.10
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Formula C6H5FO2
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Color Gray to dark gray
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SMILES
C1=C(C(=C(C=C1)F)O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 50 mg/mL (390.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (19.52 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (19.52 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (247 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.8064 mL | 39.0320 mL | 78.0640 mL | 195.1600 mL |
| 5 mM | 1.5613 mL | 7.8064 mL | 15.6128 mL | 39.0320 mL | |
| 10 mM | 0.7806 mL | 3.9032 mL | 7.8064 mL | 19.5160 mL | |
| 15 mM | 0.5204 mL | 2.6021 mL | 5.2043 mL | 13.0107 mL | |
| 20 mM | 0.3903 mL | 1.9516 mL | 3.9032 mL | 9.7580 mL | |
| 25 mM | 0.3123 mL | 1.5613 mL | 3.1226 mL | 7.8064 mL | |
| 30 mM | 0.2602 mL | 1.3011 mL | 2.6021 mL | 6.5053 mL | |
| 40 mM | 0.1952 mL | 0.9758 mL | 1.9516 mL | 4.8790 mL | |
| 50 mM | 0.1561 mL | 0.7806 mL | 1.5613 mL | 3.9032 mL | |
| 60 mM | 0.1301 mL | 0.6505 mL | 1.3011 mL | 3.2527 mL | |
| 80 mM | 0.0976 mL | 0.4879 mL | 0.9758 mL | 2.4395 mL | |
| 100 mM | 0.0781 mL | 0.3903 mL | 0.7806 mL | 1.9516 mL |
3-Fluorocatechol Related Classifications
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