PDCD4-IN-1
Based on 2 publication(s) in Google Scholar
PDCD4-IN-1(compound 20031600) is a PDCD4 inhibitor with a Kd value of 350 nM, which can promote the expression of BDNF in hippocampal neuron cell HT-22.
For research use only. We do not sell to patients.
- Purity: 99.41%
- CAS No.: 494763-64-3
- Formula: C12H9BrClN3O
- Molecular Weight:326.58
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) PDCD4-IN-1
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Biological Activity
Chemical Information
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CAS No. 494763-64-3
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Appearance Solid
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Molecular Weight 326.58
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Formula C12H9BrClN3O
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Color White to light yellow
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SMILES
O=C(C1=CC(Br)=CN=C1)NNC2=CC=CC(Cl)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Anal Chem
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing. [Abstract]2025 Jun 3;97(21):11099-11109. PMID: 40401576 -
PLoS One
Knockdown of miR-21-5P targets and regulates PDCD4-induced apoptosis in ovarian granulosa cells and ameliorates in sulin resistance in polycystic ovary syndrom. [Abstract]2026 Mar 6;21(3):e0343735. PMID: 41790840
Solvent & Solubility
DMSO : 250 mg/mL (765.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0620 mL | 15.3102 mL | 30.6204 mL | 76.5509 mL |
| 5 mM | 0.6124 mL | 3.0620 mL | 6.1241 mL | 15.3102 mL | |
| 10 mM | 0.3062 mL | 1.5310 mL | 3.0620 mL | 7.6551 mL | |
| 15 mM | 0.2041 mL | 1.0207 mL | 2.0414 mL | 5.1034 mL | |
| 20 mM | 0.1531 mL | 0.7655 mL | 1.5310 mL | 3.8275 mL | |
| 25 mM | 0.1225 mL | 0.6124 mL | 1.2248 mL | 3.0620 mL | |
| 30 mM | 0.1021 mL | 0.5103 mL | 1.0207 mL | 2.5517 mL | |
| 40 mM | 0.0766 mL | 0.3828 mL | 0.7655 mL | 1.9138 mL | |
| 50 mM | 0.0612 mL | 0.3062 mL | 0.6124 mL | 1.5310 mL | |
| 60 mM | 0.0510 mL | 0.2552 mL | 0.5103 mL | 1.2758 mL | |
| 80 mM | 0.0383 mL | 0.1914 mL | 0.3828 mL | 0.9569 mL | |
| 100 mM | 0.0306 mL | 0.1531 mL | 0.3062 mL | 0.7655 mL |
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