VCP Activator 1
Based on 2 publication(s) in Google Scholar
VCP Activator 1 is a VCP activator that dose-dependently stimulates VCP ATPase activity. VCP Activator 1 binds an allosteric pocket near the C-terminus. In addition, VCP Activator 1 binding site can also be occupied by a phenylalanine residue in the VCP C-terminal tail.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 3061959-30-3
- Formula: C20H22N2O2S
- Molecular Weight:354.47
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Cell Cycle/DNA Damage Compound Library
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Publications Citing Use of MedChemExpress (MCE) VCP Activator 1
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Biological Activity
Chemical Information
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CAS No. 3061959-30-3
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Appearance Solid
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Molecular Weight 354.47
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Formula C20H22N2O2S
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Color White to off-white
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SMILES
CCSC1=CC=CC=C1NC(C[C@@H](C)N2CC3=C(C=CC=C3)C2=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (2)
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Journal Impact Factor
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Most Recent
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bioRxiv
2025 Jan 22:2025.01.20.633888. PMID: 39896452
Solvent & Solubility
DMSO : 300 mg/mL (846.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8211 mL | 14.1056 mL | 28.2111 mL | 70.5278 mL |
| 5 mM | 0.5642 mL | 2.8211 mL | 5.6422 mL | 14.1056 mL | |
| 10 mM | 0.2821 mL | 1.4106 mL | 2.8211 mL | 7.0528 mL | |
| 15 mM | 0.1881 mL | 0.9404 mL | 1.8807 mL | 4.7019 mL | |
| 20 mM | 0.1411 mL | 0.7053 mL | 1.4106 mL | 3.5264 mL | |
| 25 mM | 0.1128 mL | 0.5642 mL | 1.1284 mL | 2.8211 mL | |
| 30 mM | 0.0940 mL | 0.4702 mL | 0.9404 mL | 2.3509 mL | |
| 40 mM | 0.0705 mL | 0.3526 mL | 0.7053 mL | 1.7632 mL | |
| 50 mM | 0.0564 mL | 0.2821 mL | 0.5642 mL | 1.4106 mL | |
| 60 mM | 0.0470 mL | 0.2351 mL | 0.4702 mL | 1.1755 mL | |
| 80 mM | 0.0353 mL | 0.1763 mL | 0.3526 mL | 0.8816 mL | |
| 100 mM | 0.0282 mL | 0.1411 mL | 0.2821 mL | 0.7053 mL |
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