DL-AP4 sodium
DL-AP4 sodium (2-Amino-4-phosphonobutyric acid sodium) is an agonist for metabotropic glutamate receptors (mGluR). DL-AP4 sodium binds to mGluR4, activates the signaling pathway that is negatively correlated with adenylate cyclase, and inhibits the Forskolin (HY-15371)-induced production of cAMP. DL-AP4 sodium is also an inhibitor for ON channel, that reduces the sensitivity of photoreceptors to brightness changes.
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- CAS No.: 1263093-79-3
- 화학식: C4H9NNaO5P
- 분자량:205.08
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
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Biological Activity
제품 설명
Chemical Information
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CAS No. 1263093-79-3
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분자량 205.08
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화학식 C4H9NNaO5P
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SMILES
OC(C(N)CCP(O)(O[Na])=O)=O
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Synonyms
2-Amino-4-phosphonobutyric acid sodium
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Thomsen C, et al., L-2-amino-4-phosphonobutyrate (L-AP4) is an agonist at the type IV metabotropic glutamate receptor which is negatively coupled to adenylate cyclase. Eur J Pharmacol. 1992 Nov 2;227(3):361-2. [Content Brief]
[2]. Dolan RP, et al., Effects of ON channel blockade with 2-amino-4-phosphonobutyrate (APB) on brightness and contrast perception in monkeys. Vis Neurosci. 1994 Jan-Feb;11(1):23-32. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DL-AP4 sodium Related Classifications
HY-110070 Related Classifications
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