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Cat. No.: HY-175316

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EGFR-IN-168

EGFR-IN-168 (Compound 9a) is a potent EGFR inhibitor with an IC₅₀ of 0.069 μM. EGFR-IN-168 has antitumor activity.

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화학식: C₂₅H₂₄FN₅O₆
분자량:509.49

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

EGFR-IN-168 Chemical Structure

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

EGFR-IN-168 (Compound 9a) is a potent EGFR inhibitor with an IC₅₀ of 0.069 μM. EGFR-IN-168 has antitumor activity^[1].

IC₅₀ & Target

69 nM (EGFR) ^[1]

All EGFR Isoforms :

Chemical Information

분자량 509.49
화학식 C₂₅H₂₄FN₅O₆
SMILES

O=C(/C=C/C1=CC=C(C=C1)F)C2=NC3=C(C=CC=C3)N2CC4=CN([C@@H]5[C@@H](O)[C@H](O)[C@H](O)[C@H](CO)O5)N=N4
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Srour AM, et al. New benzimidazole-triazole glycoconjugates as anti-cancer agents and EGFR inhibitors. Sci Rep. 2025 Jul 15;15(1):25514. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

EGFR-IN-168

All EGFR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

EGFR-IN-168 Related Classifications

HY-175316 Related Classifications