WAY-312858
Based on 1 Customer Validation
WAY-312858 is an active molecule for the study of amyloid diseases and synucleinopathies.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.0%
- No. CAS: 620570-09-4
- Fòrmula: C16H16ClFN2O3S
- Peso molecular:370.83
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Almacenamiento:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
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Help & FAQs
Actividad biológica
Descripciòn
Chemical Information
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No. CAS 620570-09-4
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Appearance Solid
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Peso molecular 370.83
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Fòrmula C16H16ClFN2O3S
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Color White to off-white
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SMILES
CCOC(N1CCN(C(C2=C(C3=CC=C(C=C3S2)F)Cl)=O)CC1)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvente y solubilidad
In Vitro:
DMSO : 66.67 mg/mL (179.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocolo
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Amyloid: Congo Red Amyloid Staining
Congo red amyloid staining is a histochemical method used to detect extracellular amyloid deposits in tissue sections based on the affinity of Congo red dye for β-pleated sheet-rich protein aggregates. When bound to amyloid, Congo red produces characteristic apple-green birefringence under polarized light microscopy, which is widely regarded as a diagnostic feature of amyloid deposition in histopathology. The diagnostic principle relies on the combination of dye binding (congophilia) and optical anisotropy under polarized illumination, which distinguishes amyloid from most non-amyloid eosinophilic extracellular deposits in routine histological evaluation. Amyloid identification by Congo red staining remains a cornerstone in diagnostic pathology despite the availability of adjunct methods such as immunohistochemistry and mass spectrometry, particularly because of its ability to localize deposits directly within tissue architecture. The specificity of Congo red-positive deposits is incre
Pureza y Documentación
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Ficha de datos (243 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6967 mL | 13.4833 mL | 26.9665 mL | 67.4163 mL |
| 5 mM | 0.5393 mL | 2.6967 mL | 5.3933 mL | 13.4833 mL | |
| 10 mM | 0.2697 mL | 1.3483 mL | 2.6967 mL | 6.7416 mL | |
| 15 mM | 0.1798 mL | 0.8989 mL | 1.7978 mL | 4.4944 mL | |
| 20 mM | 0.1348 mL | 0.6742 mL | 1.3483 mL | 3.3708 mL | |
| 25 mM | 0.1079 mL | 0.5393 mL | 1.0787 mL | 2.6967 mL | |
| 30 mM | 0.0899 mL | 0.4494 mL | 0.8989 mL | 2.2472 mL | |
| 40 mM | 0.0674 mL | 0.3371 mL | 0.6742 mL | 1.6854 mL | |
| 50 mM | 0.0539 mL | 0.2697 mL | 0.5393 mL | 1.3483 mL | |
| 60 mM | 0.0449 mL | 0.2247 mL | 0.4494 mL | 1.1236 mL | |
| 80 mM | 0.0337 mL | 0.1685 mL | 0.3371 mL | 0.8427 mL | |
| 100 mM | 0.0270 mL | 0.1348 mL | 0.2697 mL | 0.6742 mL |
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