(Z)-Broparestrol
(Z)-Broparestrol is a prostaglandin synthetase inhibitor with an IC50 of 7.0 μM in cattle. (Z)-Broparestrol inhibits prostaglandin synthetase activity in bovine seminal vesicle microsomes. (Z)-Broparestrol is applicable for acne-related research.
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- No. CAS: 22393-63-1
- Fòrmula: C22H19Br
- Peso molecular:363.29
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 22393-63-1
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Peso molecular 363.29
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Fòrmula C22H19Br
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SMILES
Br/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)\C3=CC=C(C=C3)CC
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Gilbert J, et al. Inhibition of prostaglandin synthetase by di- and triphenylethylene derivatives: a structure-activity study. Journal of medicinal chemistry. 1983 May;26(5):693-9. [Content Brief]
[2]. Toscani S, et al. Overt and hidden polymorphism in the binary system involving the Z- and E- isomers of broparestrol. Int J Pharm. 2025 Jan 25;669:125060. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)