1. Protein Tyrosine Kinase/RTK
  2. FGFR
  3. FGFR1 inhibitor-2

FGFR1 inhibitor-2 

Cat. No.: HY-139376
Handling Instructions

FGFR1 inhibitor-2 is a FGFR1 inhibitor (IC50 is 4.55 μM in MDA-MB-231 cells). FGFR1 inhibitor-2 can be used for the research of metastatic triple-negative breast cancer.

For research use only. We do not sell to patients.

FGFR1 inhibitor-2 Chemical Structure

FGFR1 inhibitor-2 Chemical Structure

CAS No. : 2410612-08-5

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Description

FGFR1 inhibitor-2 is a FGFR1 inhibitor (IC50 is 4.55 μM in MDA-MB-231 cells). FGFR1 inhibitor-2 can be used for the research of metastatic triple-negative breast cancer[1].

IC50 & Target[1]

FGFR1

 

In Vitro

FGFR1 inhibitor-2 (3 and 6 μM; 48 hours; MDA-MB-231) reduces the expression of FGFR1[1].
FGFR1 inhibitor-2 (0~5 μM; MDA-MB-231) increases the apoptotic index by 10.6-fold at 5 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: MDA-MB-231
Concentration: 3 and 6 μM
Incubation Time: 48 hours
Result: Reduced the expression of FGFR1.
Molecular Weight

507.45

Formula

C₂₅H₂₂F₅N₃O₃

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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FGFR1 inhibitor-2
Cat. No.:
HY-139376
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