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  3. Amino Acid Derivatives Biochemical Assay Reagents
  4. Fmoc-Lys(DOTA)-OH

Fmoc-Lys (DOTA)-OH is an Fmoc-protected Lysine derivative with metal-chelating properties, containing the macrocyclic chelator DOTA. Fmoc-Lys (DOTA)-OH undergoes metallation with Tb or Lu. Fmoc-Lys (DOTA)-OH utilizes metal coordination to protect the carboxyl groups of DOTA. Fmoc-Lys (DOTA)-OH can be used in solid-phase peptide synthesis research.

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Fmoc-Lys(DOTA)-OH

Fmoc-Lys(DOTA)-OH Chemical Structure

CAS No. : 1611478-62-6

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Fmoc-Lys(DOTA)-OH Related Antibodies

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Description

Fmoc-Lys (DOTA)-OH is an Fmoc-protected Lysine derivative with metal-chelating properties, containing the macrocyclic chelator DOTA. Fmoc-Lys (DOTA)-OH undergoes metallation with Tb or Lu. Fmoc-Lys (DOTA)-OH utilizes metal coordination to protect the carboxyl groups of DOTA. Fmoc-Lys (DOTA)-OH can be used in solid-phase peptide synthesis research[1].

In Vitro

Fmoc-Lys (DOTA)-OH is metallated with Tb or Lu, and the carboxyl group of DOTA is protected via metal coordination[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fmoc-Lys(DOTA)-OH Related Antibodies
Molecular Weight

754.83

Formula

C37H50N6O11
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(CN(CCN(CCN(CC1)CC(O)=O)CC(O)=O)CCN1CC(NCCCC[C@@H](C(O)=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (66.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3248 mL 6.6240 mL 13.2480 mL
5 mM 0.2650 mL 1.3248 mL 2.6496 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3248 mL 6.6240 mL 13.2480 mL 33.1200 mL
5 mM 0.2650 mL 1.3248 mL 2.6496 mL 6.6240 mL
10 mM 0.1325 mL 0.6624 mL 1.3248 mL 3.3120 mL
15 mM 0.0883 mL 0.4416 mL 0.8832 mL 2.2080 mL
20 mM 0.0662 mL 0.3312 mL 0.6624 mL 1.6560 mL
25 mM 0.0530 mL 0.2650 mL 0.5299 mL 1.3248 mL
30 mM 0.0442 mL 0.2208 mL 0.4416 mL 1.1040 mL
40 mM 0.0331 mL 0.1656 mL 0.3312 mL 0.8280 mL
50 mM 0.0265 mL 0.1325 mL 0.2650 mL 0.6624 mL
60 mM 0.0221 mL 0.1104 mL 0.2208 mL 0.5520 mL
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Fmoc-Lys(DOTA)-OH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fmoc-Lys(DOTA)-OH1611478-62-6Amino Acid DerivativesBiochemical Assay Reagentssolid phase peptide synthesisterbiumlutetiuminductively coupled plasma mass spectrometrylanthanidepeptidesICP-MStrifluoroacetic acidthiol-bearing biomoleculesDNA oligonucleotidesInhibitorinhibitorinhibit

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