Fmoc-Lys(DOTA)-OH
Based on 1 Customer Validation
Fmoc-Lys (DOTA)-OH is an Fmoc-protected Lysine derivative with metal-chelating properties, containing the macrocyclic chelator DOTA. Fmoc-Lys (DOTA)-OH undergoes metallation with Tb or Lu. Fmoc-Lys (DOTA)-OH utilizes metal coordination to protect the carboxyl groups of DOTA. Fmoc-Lys (DOTA)-OH can be used in solid-phase peptide synthesis research.
For research use only. We do not sell to patients.
- Purity: 97.06%
- CAS No.: 1611478-62-6
- Formula: C37H50N6O11
- Molecular Weight:754.83
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Fmoc-Lys (DOTA)-OH is metallated with Tb or Lu, and the carboxyl group of DOTA is protected via metal coordination[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1611478-62-6
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Appearance Solid
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Molecular Weight 754.83
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Formula C37H50N6O11
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Color White to off-white
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SMILES
OC(CN(CCN(CCN(CC1)CC(O)=O)CC(O)=O)CCN1CC(NCCCC[C@@H](C(O)=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL (66.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3248 mL | 6.6240 mL | 13.2480 mL | 33.1200 mL |
| 5 mM | 0.2650 mL | 1.3248 mL | 2.6496 mL | 6.6240 mL | |
| 10 mM | 0.1325 mL | 0.6624 mL | 1.3248 mL | 3.3120 mL | |
| 15 mM | 0.0883 mL | 0.4416 mL | 0.8832 mL | 2.2080 mL | |
| 20 mM | 0.0662 mL | 0.3312 mL | 0.6624 mL | 1.6560 mL | |
| 25 mM | 0.0530 mL | 0.2650 mL | 0.5299 mL | 1.3248 mL | |
| 30 mM | 0.0442 mL | 0.2208 mL | 0.4416 mL | 1.1040 mL | |
| 40 mM | 0.0331 mL | 0.1656 mL | 0.3312 mL | 0.8280 mL | |
| 50 mM | 0.0265 mL | 0.1325 mL | 0.2650 mL | 0.6624 mL | |
| 60 mM | 0.0221 mL | 0.1104 mL | 0.2208 mL | 0.5520 mL |