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Cat. No.: HY-10762

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FXa-IN-3

FXa-IN-3 (compound 1a) is a potent coagulation factor Xa (FXa) inhibitor with a K_i of 43 nM. FXa-IN-3 can be used in the research of thromboembolic diseases.

For research use only. We do not sell to patients.

CAS No.: 209285-82-5
Formula: C₂₀H₁₇ClN₄O₃S₂
Molecular Weight:460.95

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

FXa-IN-3 Chemical Structure

CAS No.: 209285-82-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

FXa-IN-3 (compound 1a) is a potent coagulation factor Xa (FXa) inhibitor with a K_i of 43 nM. FXa-IN-3 can be used in the research of thromboembolic diseases^[1].

Chemical Information

CAS No. 209285-82-5
Molecular Weight 460.95
Formula C₂₀H₁₇ClN₄O₃S₂
SMILES

S(N[C@@H]1C(=O)N(CC2=CC=3C(N2)=CN=CC3)CC1)(=O)(=O)C4=CC=5C(S4)=CC(Cl)=CC5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Choi-Sledeski YM, et al. Discovery of an orally efficacious inhibitor of coagulation factor Xa which incorporates a neutral P1 ligand. J Med Chem. 2003 Feb 27;46(5):681-4. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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