FXIa-IN-14
FXIa-IN-14 (Compound 14c) is a FXIa inhibitor with an IC50 value of 15 nM.
For research use only. We do not sell to patients.
- CAS No.: 2423992-72-5
- Formula: C31H29ClN4O6S
- Molecular Weight:621.10
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 15 nM (FXIa)[1].
Chemical Information
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CAS No. 2423992-72-5
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Molecular Weight 621.10
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Formula C31H29ClN4O6S
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SMILES
ClC1=CC2=C(NC(C=C2CN(C([C@H](CC3=CC=C(NC(C4C(C)C4)=O)C=C3)NC(C5=CC=C(C(O)=O)S5)=O)=O)C)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wang Y, et al. Design, synthesis and biological evaluation of 6-chloro-quinolin-2-one derivatives as novel FXIa inhibitors. Bioorg Med Chem Lett. 2024 Jan 9;99:129610. [Content Brief]
[2]. Wang Y, et al. Design, synthesis and biological evaluation of 6-chloro-quinolin-2-one derivatives as novel FXIa inhibitors[J]. Bioorganic & Medicinal Chemistry Letters, 2024, 99: 129610. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)