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Cat. No.: HY-162474

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BZG2

BZG2 is an allosteric inhibitor for the SARS-CoV-2 main protease (M^pro), with an IC₅₀ of 77 µM.

For research use only. We do not sell to patients.

Formula: C₂₀H₂₂N₄O₃
Molecular Weight:366.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

BZG2 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BZG2 is an allosteric inhibitor for the SARS-CoV-2 main protease (M^pro), with an IC₅₀ of 77 µM^[1].

Chemical Information

Molecular Weight 366.41
Formula C₂₀H₂₂N₄O₃
SMILES

O=C(C1=CC=CC=C1)N/C(NC2=CC=C([N+]([O-])=O)C=C2)=N\C3CCCCC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. de Santiago-Silva KM, et al., Molecular modelling studies and in vitro enzymatic assays identified A 4-(nitrobenzyl)guanidine derivative as inhibitor of SARS-CoV-2 Mpro. Sci Rep. 2024 Apr 14;14(1):8620. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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