Lenvervimab
Based on 1 Customer Validation
Lenvervimab (GC1102) is a IgG1-type recombinant human hepatitis B Immunoglobulin. Lenvervimab can be used for research of hepatitis B virus infection.
For research use only. We do not sell to patients.
- Purity : ≥99%
- CAS No.: 2055006-79-4
- Molecular Weight:147.526 kDa
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Storage:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Virus
IC50 & Target
HBV
In Vitro
Lenvervimab (1 nM-1 μM, 16 h) inhibits HBV infection in HepG2-NTCP cells infected with HBV[1].
Lenvervimab recognizes many viral genotypes and clinical variants of HBV infection[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HepG2-NTCP cells infected with HBV
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Concentration:1 nM-1 μM
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Incubation Time:16 h
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Result:Inhibited viral expression of the surface antigen HBsAg (hepatitis B virus surface antigen) and the core protein HBcAg.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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Human IgG1 kappa
Application
ELISA, FACS, Functional assay
Chemical Information
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CAS No. 2055006-79-4
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Appearance Liquid
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Molecular Weight 147.526 kDa
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Color Colorless to light yellow
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SMILES
[Lenvervimab]
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Synonyms
GC1102
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (257 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Jeong GU, et al. A recombinant human immunoglobulin with coherent avidity to hepatitis B virus surface antigens of various viral genotypes and clinical mutants. PLoS One. 2020 Aug 13;15(8):e0236704. [Content Brief]
[2]. Lee HW, et al. Efficacy of Lenvervimab, a Recombinant Human Immunoglobulin, in Treatment of Chronic Hepatitis B Virus Infection. Clin Gastroenterol Hepatol. 2020 Dec;18(13):3043-3045.e1. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lenvervimab Related Classifications
HY-P99693 Related Classifications
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