Streptavidin
Based on 5 publication(s) in Google Scholar
Streptavidin is a ~60 kDa homotetramer. Streptavidin binds four molecules of biotin with the highest affinity. The binding affinity of biotin to streptavidin is one of the highest reported for a non-covalent interaction to date, with a KD ~0.01 pM. Streptavidin has an immunosuppressive role.
This product is a Streptavidin protein recombinantly expressed in an E. coli expression system.
For research use only. We do not sell to patients.
- Purity: 98.5%
- CAS No.: 9013-20-1
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Streptavidin
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Biological Activity
This product is a Streptavidin protein recombinantly expressed in an E. coli expression system.
Streptavidin (2-200 μg/mL) significantly suppresses the proliferation of Lewis T cells to WF by 76%-83% compared with untreated responders[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Lewis T cells
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Concentration:2-200 μg/mL
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Incubation Time:
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Result:Inhibited the proliferation of Lewis T cells to WF stimulators by 76%-83% compared with untreated responders, lower concentrations of 0.1 and 0.2 μg/mL did not significantly inhibit T-cell proliferation.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Lewis rats[2]
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Dosage:8, 12, 20, 40, 60, or 80 mg/kg
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Administration:Administered IP for 5 consecutive days after transplantation was combined with a single dose of 0.5 mL antilymphocyte serum (ALS) on day 0
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Result:Prolonged cardiac allograft survival from MST of 7.3±0.5 and 8.4±0.5 days in naive and ALS-treated controls, respectively, to 15±1, 20±3, 16±3, 17±3, and 23±2 days, respectively.
Chemical Information
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CAS No. 9013-20-1
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Appearance Solid
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Color White to off-white
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SMILES
[Streptavidin]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (5)
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Journal Impact Factor
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Most Recent
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Ann Rheum Dis
Generation of cytotoxic aptamers specifically targeting fibroblast-like synoviocytes by CSCT-SELEX for treatment of rheumatoid arthritis. [Abstract]2024 Sep 4:ard-2024-225565. PMID: 39237134 -
ACS Nano
Nanoparticle Size Influences the Self-Assembly of Gold Nanorods Using Flexible Streptavidin-Biotin Linkages. [Abstract]2023 Dec 12;17(23):24090-24103. PMID: 38010073 -
Alzheimers Res Ther
Novel fully human high-affinity anti-TREM2 antibody shows efficacy in clinically relevant Alzheimer´s mouse model. [Abstract]2025 May 22;17(1):114. PMID: 40405265 -
Br J Cancer
SLC7A11-AS1 contributes to prolonged activation of activin A/Smad signaling by suppressing PPM1A myristoylation in pancreatic cancer. [Abstract]2025 Sep 9. PMID: 40926062 -
Anal Chim Acta
A highly sensitive magnetic separation-assisted electrochemical sensor for detection of m6A-microRNA-17-5p based on rolling circle amplification and N3-kethoxal labeling strategy at LIG electrodes. [Abstract]2025 Dec 1:1377:344655. PMID: 41093520
Solvent & Solubility
H2O : 100 mg/mL (Need ultrasonic)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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