AMBA
AMBA is a gastrin-releasing peptide receptor (GRPR, BB2, BRS-2) ligand. AMBA binds to GRPR with high specificity and high affinity, and undergoes receptor-mediated endocytosis, which retains the conjugated radiometal in target cells. AMBA is applicable for the research of prostate cancer.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 721937-56-0
- Fòrmula: C68H99N19O18S
- Peso molecular:1502.70
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Descripciòn
In Vitro
AMBA (0.001-1000 nmol/L; 60 min) exhibits high specificity and nanomolar affinity for human GRPR receptors, with an IC50 of 0.82 nmol/L and a Ki of 0.65nmol/L[1].
AMBA (6.66 × 10-4 μmol (1 μg); 10 min) can be efficiently radiolabeled with 111In, achieving a radiolabeling efficiency of 95.43% under the tested conditions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 721937-56-0
-
Peso molecular 1502.70
-
Fòrmula C68H99N19O18S
-
Sequence
{DOTA}-Gly-{PAB}-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
-
Sequence Shortening
{DOTA}-G-{PAB}-QWAVGHLM-NH2
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AMBA Related Classifications
HY-P11768 Related Classifications
Powered by Bioz