Bleomycin B2
Bleomycin B2 (Phleomycin D2) is an anti-cancer agent that targets DNA. Bleomycin B2 causes DNA strand breaks, thereby inhibiting the growth and proliferation of cancer cells. Bleomycin B2 is promising for research of cancers.
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- No. CAS: 9060-10-0
- Fòrmula: C55H84N20O21S2
- Peso molecular:1425.51
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 9060-10-0
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Peso molecular 1425.51
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Fòrmula C55H84N20O21S2
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SMILES
O=C(C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C)N[C@H](C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@@H]([C@H](O)C)C(NCCC2=NC(C3=NC(C(NCCCCNC(N)=N)=O)=CS3)=CS2)=O)=O)=O)[C@H](C4=CN=CN4)O[C@H]5[C@H]([C@H]([C@@H]([C@@H](O5)CO)O)O)O[C@@H]6[C@H]([C@H]([C@@H]([C@H](O6)CO)O)OC(N)=O)O
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Synonyms
Phleomycin D2
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Structure Classification
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Initial Source
Streptomyces verticillus
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bleomycin B2 Related Classifications
HY-W749297 Related Classifications
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