DPPC-13C2
Based on 1 publication(s) in Google Scholar
DPPC-13C2 is a deuterated labeled DPPC. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice.
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- Pureza: 95.0%
- No. CAS: 65277-91-0
- Fòrmula: C3813C2H80NO8P
- Peso molecular:736.02
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Almacenamiento:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) DPPC-13C2
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Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 65277-91-0
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Unlabeled Cas 63-89-8
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Appearance Solid
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Peso molecular 736.02
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Fòrmula C3813C2H80NO8P
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Color White to off-white
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SMILES
CCCCCCCCCCCCCCC[13C](O[C@H](CO[13C](CCCCCCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O
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Synonyms
129Y83-13C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Biomed Mater
Multi-functionalized magnetic nanoparticles can be used for targeted therapy and diagnosis of lung cancer. [Abstract]2026 Mar 19;21(2). PMID: 41812273
Solvente y solubilidad
Ethanol : 25 mg/mL (33.97 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811. [Content Brief]
[3]. Akiko Uemura, et al. Induction of immune responses against glycosphingolipid antigens: comparison of antibody responses in mice immunized with antigen associated with liposomes prepared from various phospholipids. J Vet Med Sci. 2005 Dec;67(12):1197-201. [Content Brief]
[4]. Ege C, et al. Insertion of Alzheimer's A beta 40 peptide into lipid monolayers. Biophys J. 2004 Sep;87(3):1732-40. [Content Brief]
[5]. Kalra VK, et al. Transport of amino acids in gamma-glutamyl transpeptidase-implanted human erythrocytes. J Biol Chem. 1981 Jun 10;256(11):5567-71. [Content Brief]
[6]. Leekumjorn S, et al. Molecular simulation study of structural and dynamic properties of mixed DPPC/DPPE bilayers. Biophys J. 2006 Jun 1;90(11):3951-65. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 1.3587 mL | 6.7933 mL | 13.5866 mL | 33.9665 mL |
| 5 mM | 0.2717 mL | 1.3587 mL | 2.7173 mL | 6.7933 mL | |
| 10 mM | 0.1359 mL | 0.6793 mL | 1.3587 mL | 3.3966 mL | |
| 15 mM | 0.0906 mL | 0.4529 mL | 0.9058 mL | 2.2644 mL | |
| 20 mM | 0.0679 mL | 0.3397 mL | 0.6793 mL | 1.6983 mL | |
| 25 mM | 0.0543 mL | 0.2717 mL | 0.5435 mL | 1.3587 mL | |
| 30 mM | 0.0453 mL | 0.2264 mL | 0.4529 mL | 1.1322 mL |
DPPC-13C2 Related Classifications
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