MLS-0053105
Based on 1 Customer Validation
MLS-0053105, a chloromaleimide, is a selective BFL-1 inhibitor with an IC50 of 0.4 µM for Bfl-1/F-Bid. MLS-0053105 shows over 10 times less potent inhibition of Bcl-W, Bcl-2, and Bcl-XL and no activity against Bcl-B and Mcl-1.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.89%
- No. CAS: 370572-36-4
- Fòrmula: C15H14Cl3N3O2
- Peso molecular:374.65
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Almacenamiento:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
Bfl-1/F-Bid 0.4 μM (IC50) |
Bcl-W/F-Bim 12.5 μM (IC50) |
Bcl-2/F-Bim 12.5 μM (IC50) |
Bcl-XL/F-Bim 50 μM (IC50) |
Chemical Information
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No. CAS 370572-36-4
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Appearance Solid
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Peso molecular 374.65
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Fòrmula C15H14Cl3N3O2
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Color Yellow to orange
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SMILES
O=C1C(Cl)=C(N2CCN(CC2)C)C(N1C3=CC=C(C(Cl)=C3)Cl)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Pureza y Documentación
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Ficha de datos (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MLS-0053105 Related Classifications
HY-167881 Related Classifications
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