MS1 peptide
MS-1 peptide is a peptide for BH3 profiling. MS-1 peptide triggers higher depolarization of mitochondrial membrane in melanoma cells pre-treated with Encorafenib (HY-15605). MS1 peptide can be used for the research of BRAFV600E melanoma.
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- No. CAS: 1875102-20-7
- Fòrmula: C126H197N39O35S
- Peso molecular:2850.22
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
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Bcl-2 |
MS1 peptide (4-8 μM) significantly increases mitochondrial membrane depolarization in encorafenib-pretreated DMBC11, DMBC12, DMBC21, DMBC28, and DMBC29 BRAFV600E melanoma cells, indicating altered cell dependence on anti-apoptotic proteins after encorafenib exposure[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1875102-20-7
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Peso molecular 2850.22
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Fòrmula C126H197N39O35S
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Sequence
Ac-Arg-Pro-Glu-Ile-Trp-Met-Thr-Gln-Gly-Leu-Arg-Arg-Leu-Gly-Asp-Glu-Ile-Asn-Ala-Tyr-Tyr-Ala-Arg-NH2
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Sequence Shortening
Ac-RPEIWMTQGLRRLGDEINAYYAR-NH2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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