MS1 peptide
Based on 1 Customer Validation
MS-1 peptide is a peptide for BH3 profiling. MS-1 peptide triggers higher depolarization of mitochondrial membrane in melanoma cells pre-treated with Encorafenib (HY-15605). MS1 peptide can be used for the research of BRAFV600E melanoma.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.57%
- No. CAS: 1875102-20-7
- Fòrmula: C126H197N39O35S
- Peso molecular:2850.22
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Almacenamiento:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
Bcl-2 |
In Vitro
MS1 peptide (4-8 μM) significantly increases mitochondrial membrane depolarization in encorafenib-pretreated DMBC11, DMBC12, DMBC21, DMBC28, and DMBC29 BRAFV600E melanoma cells, indicating altered cell dependence on anti-apoptotic proteins after encorafenib exposure[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1875102-20-7
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Appearance Solid
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Peso molecular 2850.22
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Fòrmula C126H197N39O35S
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Color White to off-white
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Sequence
Ac-Arg-Pro-Glu-Ile-Trp-Met-Thr-Gln-Gly-Leu-Arg-Arg-Leu-Gly-Asp-Glu-Ile-Asn-Ala-Tyr-Tyr-Ala-Arg-NH2
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Sequence Shortening
Ac-RPEIWMTQGLRRLGDEINAYYAR-NH2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvente y solubilidad
In Vitro:
H2O : 2.5 mg/mL (0.88 mM; Need ultrasonic)
Pureza y Documentación
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Ficha de datos (272 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MS1 peptide Related Classifications
HY-P11706 Related Classifications
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