NU-8231
NU-8231 (Compound 2) is a p53-MDM2 binding inhibitor with an IC50 of 5.3-200 μM for inhibiting the p53-MDM2 interaction. NU-8231 is applicable for cancer research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 878022-36-7
- Fòrmula: C26H26ClNO5
- Peso molecular:467.95
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| SJSA-1 | IC50 |
5.3 μM
Compound: 2q
|
Inhibitory concentration against MDM2-p53 interaction in SJSA human sarcoma cells
Inhibitory concentration against MDM2-p53 interaction in SJSA human sarcoma cells
|
[PMID: 15713419] |
Chemical Information
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No. CAS 878022-36-7
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Peso molecular 467.95
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Fòrmula C26H26ClNO5
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SMILES
O=C1C=2C=CC=CC2C(OCC3=CC(OC)=C(O)C(OC)=C3)(C4=CC=C(Cl)C=C4)N1CCC
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)