NU-8231
NU-8231 (Compound 2) is a p53-MDM2 binding inhibitor with an IC50 of 5.3-200 μM for inhibiting the p53-MDM2 interaction. NU-8231 is applicable for cancer research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 878022-36-7
- Fòrmula: C26H26ClNO5
- Peso molecular:467.95
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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- Pureza y Documentación
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Help & FAQs
Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| SJSA-1 | IC50 |
5.3 μM
Compound: 2q
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Inhibitory concentration against MDM2-p53 interaction in SJSA human sarcoma cells
Inhibitory concentration against MDM2-p53 interaction in SJSA human sarcoma cells
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[PMID: 15713419] |
Chemical Information
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No. CAS 878022-36-7
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Peso molecular 467.95
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Fòrmula C26H26ClNO5
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SMILES
O=C1C=2C=CC=CC2C(OCC3=CC(OC)=C(O)C(OC)=C3)(C4=CC=C(Cl)C=C4)N1CCC
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NU-8231 Related Classifications
HY-119014 Related Classifications
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