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Referencia número: HY-155620

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PD10

PD10 is an AChE and BuChE inhibitor (hAChE IC₅₀: 0.56 μM; eeAChE IC₅₀: 0.59 μM; eqBuChE IC₅₀: 1.06 μM). PD10 can be used for research of Alzheimer’s disease.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₂₃H₂₁BrN₂O₄
Peso molecular:469.33

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

PD10 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

PD10 is an AChE and BuChE inhibitor (hAChE IC₅₀: 0.56 μM; eeAChE IC₅₀: 0.59 μM; eqBuChE IC₅₀: 1.06 μM). PD10 can be used for research of Alzheimer’s disease^[1].

IC₅₀ & Target

0.56 μM, 0.59 μM, 1.06 μM (hAChE, eeAChE, eqBuChE)^[1]

Ver todos los productos específicos de isoformas Cholinesterase (ChE) :

AChE
BChE

Chemical Information

Peso molecular 469.33
Fòrmula C₂₃H₂₁BrN₂O₄
SMILES

O=C(N1CCN(C(C2=CC=C(Br)C=C2)=O)CC1)/C=C/C=C/C3=CC=C(OCO4)C4=C3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Bhanukiran K, et al. Discovery of Multitarget-Directed Ligands from Piperidine Alkaloid Piperine as a Cap Group for the Management of Alzheimer's Disease. ACS Chem Neurosci. 2023 Aug 2;14(15):2743-2760. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias

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PD10

Ver todos los productos específicos de isoformas Cholinesterase (ChE)

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

PD10 Related Classifications

HY-155620 Related Classifications