Sordarin
Sordarin (Compound 1) is an antifungal agent targeting Elongation factor 2 (EF2) with a tetracyclic diterpene core including a norbornene system. Sordarin can be isolated from the fungus Sordaria araneosa. Sordarin has potent antifungal activity against Saccharomyces cerevisiae and Candida albicans. Sordarin prevents the translocation of the ribosome along mRNA during elongation of the emerging polypeptide chain, inhibiting protein synthesis in fungi by stabilizing the ribosome/EF2 complex.
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- No. CAS: 11076-17-8
- Fòrmula: C27H40O8
- Peso molecular:492.60
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 11076-17-8
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Peso molecular 492.60
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Fòrmula C27H40O8
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SMILES
OC([C@@]1([C@@]([C@@]2([H])[C@]([C@@H](CC2)C)([H])C3)(C4)C=O)[C@]3([C@@]4([H])C=C1C(C)C)CO[C@@H]5O[C@@H]([C@H]([C@H]([C@@H]5O)O)OC)C)=O
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Structure Classification
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Initial Source
Sordaria araneosa
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sordarin Related Classifications
HY-128478 Related Classifications
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