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Referencia número: HY-P99582

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Biologically Validated

Tabituximab

Name: Tabituximab
Brand: MedChemExpress
SKU: HY-P99582
Price: 485.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: ONC-005, OTSA101)

Revisión del cliente

Based on 1 Customer Validation

Tabituximab (OTSA101) is a humanized monoclonal antibody against frizzled class receptor 10 (FZD10).

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza : ≥99.0%
No. CAS: 1644134-10-0
Peso molecular:144.64 kDa

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Tabituximab Chemical Structure

No. CAS: 1644134-10-0

Tamaño

Precio

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- In Vivo
- Gene ID
- Accession
- Conjugated
- Reconsititution
- Format
- Aplicación
- Verified Bioactivity
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Tabituximab (OTSA101) is a humanized monoclonal antibody against frizzled class receptor 10 (FZD10)^[1].

Isotype

Human IgG1 kappa

Recommend Isotype Controls

Human IgG1 kappa, Isotype Control

Species Reactivity

Human

IC₅₀ & Target

FZD10

In Vitro

Non-radiolabeled Tabituximab (OTSA101) antibody has only weak antagonistic activity on synovial sarcoma cell growth^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

In Vivo

Yttrium 90-radiolabeled OTSA101 (OTSA101-DTPA-90Y) shows significant antitumor activity following a single intravenous injection in mouse xenograft model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gene ID

11211 [NCBI]

Accession

Q9ULW2

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

Human IgG1 kappa

Aplicación

ELISA, FACS, Functional assay

Verified Bioactivity

Immobilized Frizzled-10/CD350 Protein, Human (HEK293, His, HY-P74146) can bind Tabituximab. The EC₅₀ for this effect is 2.961 ng/mL.

Chemical Information

No. CAS 1644134-10-0
Appearance Liquid
Peso molecular 144.64 kDa
Color Colorless to light yellow
SMILES

[Tabituximab]
Synonyms

ONC-005, OTSA101
Envío

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (255 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Inhibitory Antibodies User Guide (603 KB)

Referencias

[1]. Blagodatski A, et al. Targeting the Wnt pathways for therapies. Mol Cell Ther. 2014 Sep 11;2:28. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Actividad biológica
- Descripciòn
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- In Vivo
- Gene ID
- Accession
- Conjugated
- Reconsititution
- Format
- Aplicación
- Biological Activity
Chemical Information
Pureza y Documentación
Referencias

Nombre del producto:
Referencia número:
Cantidad:
MCE Japan Authorized Agent:

Nombre del producto:
No. CAS:
Species:
Pureza:
Cantidad:

Tabituximab

Cell-ATP Viability Detection Kit

HOLO Human Interleukin-2 (IL-2) Detection Kit

Protein A Agarose

Bradford Protein Assay Kit

DPBS Buffer (1×)

Cytotoxicity LDH Assay Kit

PBS Buffer (1×)