CIROP - ciliated left-right organizer metallopeptidase Gene

Also Known as HTX12; LMLN2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 100128908

About CIROP

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:23,099,062-23,104,989 (from NCBI)

This gene has 4 transcripts (splice variants), 54 orthologues and is associated with 1 phenotype. Low expression observed in reference dataset.

Summary

Predicted to enable peptidase activity. Predicted to be involved in cell adhesion and proteolysis. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CIROP Products (2)

mRNA Protein Name
NM_001354640.2 NP_001341569.1 ciliated left-right organizer metallopeptidase isoform 1 precursor
NM_001402427.1 NP_001389356.1 ciliated left-right organizer metallopeptidase isoform 2 precursor
Protein Preferred Names Protein Names

ciliated left-right organizer metallopeptidase

  • leishmanolysin homolog

Related Diseases

Diseases Alias
Heterotaxy, Visceral, 12, Autosomal
  • HTX12

Visceral Heterotaxy
  • Situs Ambiguus

  • Heterotaxia

  • Heterotaxy Syndrome

  • Heterotaxy

  • Lateralization Defect

  • Situs Ambiguous

  • Left Isomerism

  • Htx

  • Ivemark Syndrome

  • Right Isomerism

  • Situs Ambiguus Viscerum

  • Incomplete Situs Inversus

  • Partial Situs Inversus

  • Heterotaxy, Visceral

  • Asplenia Syndrome

  • Bilateral Left-Sidedness

  • Polysplenia Syndrome

  • Moller Syndrome

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CIROP RGD RGD:1560492
Canis familiaris CIROP VGNC VGNC:108383
Macaca mulatta CIROP VGNC VGNC:108382
Mus musculus CIROP MGD MGI:5588935