Fhod3 - formin homology 2 domain containing 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 100360334

Summary

Predicted to enable actin filament binding activity. Acts upstream of or within sarcomere organization. Located in striated muscle thin filament. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy. Orthologous to human FHOD3 (formin homology 2 domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Fhod3 Products (1)

mRNA Protein Name
NM_001271332.3 NP_001258261.3 FH1/FH2 domain-containing protein 3

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within sarcomere organization IMP
IMP: Inferred from mutant phenotype
19706596 RGD
Cellular Component GO Annotation Evidence References Source
located in striated muscle thin filament IDA
IDA: Inferred from direct assay
19706596 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

FH1/FH2 domain-containing protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04939 FHOD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05004 FMNL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22507 Fhod3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29028 Fhod3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fhod3 NCBI NCBI:80206