Kifc1 - kinesin family member C1 Gene

Also Known as HSET; KNSL2; Gm4137; Kifc5a; Knsl2a; Tctex7; Tctex-7; Tctex7a; Tctex-7A; 100042970

Species: Mus musculus

Gene Type: protein coding
Gene ID: 100502766

Summary

Enables minus-end-directed microtubule motor activity. Acts upstream of or within minus-end-directed vesicle transport along microtubule and negative regulation of centrosome duplication. Located in endocytic vesicle; nucleus; and spindle. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. [provided by Alliance of Genome Resources, Apr 2022]

Kifc1 Products (5)

mRNA Protein Name
NM_001195298.1 NP_001182227.1 kinesin-like protein KIFC1 isoform 1
NM_001410585.1 NP_001397514.1 kinesin-like protein KIFC1 isoform 2
NM_001410586.1 NP_001397515.1 kinesin-like protein KIFC1 isoform 3
NM_001410587.1 NP_001397516.1 kinesin-like protein KIFC1 isoform 4
NM_001410588.1 NP_001397517.1 kinesin-like protein KIFC1 isoform 4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables minus-end-directed microtubule motor activity IDA
IDA: Inferred from direct assay
16638812 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16638812 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within minus-end-directed vesicle transport along microtubule IMP
IMP: Inferred from mutant phenotype
17360972 MGI
acts upstream of or within negative regulation of centrosome duplication IMP
IMP: Inferred from mutant phenotype
16638812 MGI
acts upstream of or within vesicle transport along microtubule IGI
IGI: Inferred from genetic interaction
17360972 MGI
Cellular Component GO Annotation Evidence References Source
located in endocytic vesicle IDA
IDA: Inferred from direct assay
17360972 MGI
located in mitotic spindle IDA
IDA: Inferred from direct assay
16638812 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16638812 MGI
located in spindle pole centrosome IDA
IDA: Inferred from direct assay
16638812 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kinesin-like protein KIFC1

  • kinesin family c-terminal 5A

  • kinesin motor protein KIFC4

  • kinesin-like 2a

  • kinesin-related protein KIFC5A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12241 AZ82 Inhibitor 99.86% Unkown
HY-118961 SR31527 chloride Inhibitor 97.35% Unkown
HY-RS07298 KIFC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-180304 CCT369834 Inhibitor / Unkown
HY-N11128 Solidagonic acid Inhibitor / Unkown
HY-RS19017 Kifc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25506 Kifc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kifc1 NCBI NCBI:3833