Acacb - acetyl-Coenzyme A carboxylase beta Gene

Also Known as Acc2; Accb

Species: Mus musculus

Gene Type: protein coding
Gene ID: 100705

Summary

Enables Acetyl-CoA Carboxylase activity. Involved in several processes, including energy homeostasis; malonyl-CoA biosynthetic process; and negative regulation of fatty acid beta-oxidation. Acts upstream of or within fatty acid biosynthetic process. Located in mitochondrion. Is expressed in axial skeleton; cranium; and liver. Orthologous to human ACACB (Acetyl-CoA Carboxylase beta). [provided by Alliance of Genome Resources, Apr 2022]

Acacb Products (4)

mRNA Protein Name
NM_001403527.1 NP_001390456.1 acetyl-CoA carboxylase 2 isoform 1 precursor
NM_001403528.1 NP_001390457.1 acetyl-CoA carboxylase 2 isoform 3
NM_001403529.1 NP_001390458.1 acetyl-CoA carboxylase 2 isoform 4
NM_133904.3 NP_598665.2 acetyl-CoA carboxylase 2 isoform 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acetyl-CoA carboxylase activity IDA
IDA: Inferred from direct assay
17210641 MGI
enables acetyl-CoA carboxylase activity IMP
IMP: Inferred from mutant phenotype
17210641 MGI
Biological Process GO Annotation Evidence References Source
involved in energy homeostasis IMP
IMP: Inferred from mutant phenotype
12920182 MGI
acts upstream of or within fatty acid biosynthetic process IMP
IMP: Inferred from mutant phenotype
17210641 MGI
involved in malonyl-CoA biosynthetic process IMP
IMP: Inferred from mutant phenotype
18487439 MGI
involved in negative regulation of fatty acid beta-oxidation IMP
IMP: Inferred from mutant phenotype
12920182 MGI
involved in negative regulation of fatty acid oxidation IMP
IMP: Inferred from mutant phenotype
11283375 MGI
involved in negative regulation of lipid catabolic process IMP
IMP: Inferred from mutant phenotype
15677334 MGI
involved in positive regulation of heart growth IMP
IMP: Inferred from mutant phenotype
18487439 MGI
involved in positive regulation of lipid storage IMP
IMP: Inferred from mutant phenotype
11283375 MGI
involved in regulation of glucose metabolic process IMP
IMP: Inferred from mutant phenotype
15677334 MGI
involved in response to nutrient levels IMP
IMP: Inferred from mutant phenotype
12920182 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
10677481 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acetyl-CoA carboxylase 2

  • ACC-beta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00122 ACACB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20357 Acacb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26866 Acacb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acacb NCBI NCBI:32