RPP38 - ribonuclease P/MRP subunit p38 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10557

Summary

Enables ribonuclease P RNA binding activity. Contributes to ribonuclease P activity. Involved in tRNA 5'-leader removal. Located in nucleolus. Part of multimeric ribonuclease P complex. [provided by Alliance of Genome Resources, Jun 2026]
Broad expression in testis (RPKM 13.4), lymph node (RPKM 4.9) and 25 other tissues.

RPP38 Products (4)

mRNA Protein Name
NM_001097590.3 NP_001091059.1 ribonuclease P protein subunit p38
NM_001265601.2 NP_001252530.1 ribonuclease P protein subunit p38
NM_006414.5 NP_006405.2 ribonuclease P protein subunit p38
NM_183005.5 NP_892117.1 ribonuclease P protein subunit p38

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15096576 GOA
enables ribonuclease P RNA binding IDA
IDA: Inferred from direct assay
30454648 GOA
contributes to ribonuclease P activity IDA
IDA: Inferred from direct assay
30454648 GOA
Biological Process GO Annotation Evidence References Source
involved in tRNA 5'-leader removal IDA
IDA: Inferred from direct assay
30454648 GOA
Cellular Component GO Annotation Evidence References Source
part of multimeric ribonuclease P complex IDA
IDA: Inferred from direct assay
30454648 GOA
located in nucleolus IDA
IDA: Inferred from direct assay
10444065 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RPP38 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RPP38 P78345 POP4 Homo sapiens O95707
Pull Down
15096576
Intra
RPP38 P78345 NCK1 Homo sapiens P16333
Peptide Array
17474147
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12195 RPL38 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12215 RPP30 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22786 Rpl38 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29300 Rpl38 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown