Pi4kb - phosphatidylinositol 4-kinase beta Gene

Also Known as ESTM41; Pik4cb; PI4Kbeta; PI4K-beta

Species: Mus musculus

Gene Type: protein coding
Gene ID: 107650

About Pi4kb

Chromosome 3: 94,882,042-94,914,154 forward strand.GRCm39:CM000996.3

This gene has 7 transcripts (splice variants), 213 orthologues and 9 paralogues. Ubiquitous expression in subcutaneous fat pad adult (RPKM 17.1), bladder adult (RPKM 16.1) and 28 other tissues.

Summary

Predicted to enable 1-phosphatidylinositol 4-kinase activity and 14-3-3 protein binding activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and phosphatidylinositol-mediated signaling. Predicted to be located in Golgi membrane; cytosol; and plasma membrane. Predicted to be active in cytoplasm and membrane. Is expressed in vertebral axis musculature. Orthologous to human PI4KB (phosphatidylinositol 4-kinase beta). [provided by Alliance of Genome Resources, Apr 2022]

Pi4kb Products (3)

mRNA Protein Name
NM_001293715.1 NP_001280644.1 phosphatidylinositol 4-kinase beta isoform 1
NM_175356.3 NP_780565.2 phosphatidylinositol 4-kinase beta isoform 2
NM_001293716.1 NP_001280645.1 phosphatidylinositol 4-kinase beta isoform 3

Pi4kb Protein Structure

PI4KB_NTD

PI4KB_NTD: cd22246 (1 - 65)

PI4Kc_III_beta

PI4Kc_III_beta: cd05168 (513 - 800)

  • 0
  • 200
  • 400
  • 600
  • 801 a.a.
Protein Preferred Names Protein Names

phosphatidylinositol 4-kinase beta

  • phosphatidylinositol 4-kinase, catalytic, beta polypeptide

  • ptdIns 4-kinase beta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100603 GSK-F1 Inhibitor 95.06% Unkown
HY-108313 T-00127_HEV1 Inhibitor 99.97% Unkown
HY-22055B AN-12-H5 intermediate-1 99.72% Unkown
HY-W047496 AN-12-H5 intermediate-2 97.0% Unkown
HY-120900 AN-12-H5 Inhibitor 98.03% Unkown
HY-RS10470 Pi4kb Mouse Pre-designed siRNA Set A / Unkown
HY-177725 MG degrader 2 Degrader / Unkown
HY-182721 Pipinib / Unkown
HY-RS10469 PI4KB Human Pre-designed siRNA Set A / Unkown
HY-RS10471 Pi4kb Rat Pre-designed siRNA Set A / Unkown
HY-100603B (R)-GSK-F1 Inhibitor / Unkown
HY-175557 PI4K-IN-2 Inhibitor / Unkown
HY-W451820 AN-12-H5 intermediate-3 95.82% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pi4kb NCBI NCBI:5298