Abcg1 - ATP binding cassette subfamily G member 1 Gene

Also Known as Abc8; White

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11307

Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The human protein is involved in macrophage Cholesterol efflux and may regulate cellular lipid homeostasis in Other cell types. [provided by RefSeq, Jul 2008]

Abcg1 Products (1)

mRNA Protein Name
NM_009593.2 NP_033723.1 ATP-binding cassette sub-family G member 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to high density lipoprotein particle stimulus IDA
IDA: Inferred from direct assay
15210959 MGI
involved in cholesterol efflux IMP
IMP: Inferred from mutant phenotype
16556852 MGI
acts upstream of or within cholesterol transport IDA
IDA: Inferred from direct assay
15319426 MGI
involved in high-density lipoprotein particle remodeling IMP
IMP: Inferred from mutant phenotype
16556852 MGI
involved in low-density lipoprotein particle remodeling IMP
IMP: Inferred from mutant phenotype
16556852 MGI
involved in negative regulation of lipid storage IMP
IMP: Inferred from mutant phenotype
16556852 MGI
involved in positive regulation of cholesterol biosynthetic process IMP
IMP: Inferred from mutant phenotype
17916878 MGI
involved in positive regulation of cholesterol efflux IDA
IDA: Inferred from direct assay
15210959 MGI
involved in regulation of cholesterol metabolic process IMP
IMP: Inferred from mutant phenotype
16556852 MGI
involved in reverse cholesterol transport IMP
IMP: Inferred from mutant phenotype
17657311 MGI
Cellular Component GO Annotation Evidence References Source
located in endosome IDA
IDA: Inferred from direct assay
17916878 MGI
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
16556852 MGI
located in recycling endosome IDA
IDA: Inferred from direct assay
16556852 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-binding cassette sub-family G member 1

  • ATP-binding cassette 8

  • ATP-binding cassette transporter 8

  • ATP-binding cassette, sub-family G (WHITE), member 1

  • white protein homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W020012 Fluoresterol 99.65% Unkown
HY-18282 AZ876 Agonist 99.77% Unkown
HY-123148 IMB-808 Agonist 99.84% Unkown
HY-NP203 High density lipoprotein (human) Activator 98.00% Unkown
HY-W674245 10-Hydroxyhexadecanoic acid 99.53% Unkown
HY-RS17499 Abcg1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00076 ABCG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-115780 E17110 Agonist / Unkown
HY-121671 TBTC Activator 97.22% Unkown
HY-179535 Axl-IN-21 Inhibitor / Unkown
HY-181509 TNF-α/IL-1β/IL-6-IN-1 / Unkown
HY-186045 SKLB06489 / Unkown
HY-184337 Dihydroparadol / Unkown
HY-RS23956 Abcg1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abcg1 NCBI NCBI:9619