Aebp2 - AE binding protein 2 Gene

Also Known as B230313N05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11569

Summary

Enables transcription coregulator activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of transcription, DNA-templated. Located in nucleus. Part of ESC/E(Z) complex. Is expressed in autopod; brain; early conceptus; genitourinary system; and gut. Used to study Hirschsprung's disease and Waardenburg's syndrome. Orthologous to human AEBP2 (AE binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Aebp2 Products (5)

mRNA Protein Name
NM_001005605.3 NP_001005605.1 zinc finger protein AEBP2 isoform 1
NM_001309436.2 NP_001296365.1 zinc finger protein AEBP2 isoform 4
NM_001309437.1 NP_001296366.1 zinc finger protein AEBP2 isoform 4
NM_009637.5 NP_033767.2 zinc finger protein AEBP2 isoform 3
NM_178803.3 NP_848918.1 zinc finger protein AEBP2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables transcription coregulator activity IDA
IDA: Inferred from direct assay
10329662 MGI
enables transcription coregulator activity IMP
IMP: Inferred from mutant phenotype
10329662 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
10329662 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
10329662 MGI
Cellular Component GO Annotation Evidence References Source
part of ESC/E(Z) complex IDA
IDA: Inferred from direct assay
20064375 MGI
located in nucleus IDA
IDA: Inferred from direct assay
10329662 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger protein AEBP2

  • adipocyte enhancer-binding protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-174372 EZH2-IN-23 Inhibitor / Unkown
HY-RS00423 AEBP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22380 Aebp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28904 Aebp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aebp2 NCBI NCBI:121536