1. Gene
  2. Calcr - calcitonin receptor Gene

Calcr - calcitonin receptor Gene

Rattus norvegicus
Gene ID: 116506 | Gene type: protein coding

About Calcr

Primary_assembly 4: 31,661,273-31,736,392 reverse strand.mRatBN7.2:CM026977.1

This gene has 2 transcripts (splice variants), 218 orthologues, 42 paralogues and is associated with 4 phenotypes. Biased expression in Kidney (RPKM 27.7), Brain (RPKM 15.8) and 1 other tissue.

Summary

Enables Calcitonin binding activity and Calcitonin receptor activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Located in axon and neuronal cell body. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to human CALCR (Calcitonin receptor). [provided by Alliance of Genome Resources, Apr 2022]

Calcr Products(2)

mRNA Protein Name
NM_053816.2 NP_446268.2 calcitonin receptor isoform 1b precursor
NM_001034015.1 NP_001029187.1 calcitonin receptor isoform 1a precursor

Calcr Protein Structure

HRM

HRM: pfam02793 (85 - 153)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (161 - 471)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (163 - 188)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (197 - 219)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (273 - 300)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (312 - 332)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (347 - 376)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (390 - 417)

7tmB1_calcitonin_R

7tmB1_calcitonin_R: cd15274 (423 - 448)

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  • 533 a.a.
Protein Preferred Names Protein Names

calcitonin receptor

C1A/C1B

CT-R

Orthologs Information

Species Symbol Source ID
Homo sapiens Calcr NCBI NCBI:799