S100a8 - S100 calcium binding protein A8 Gene

Also Known as Mrp8

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116547

Summary

Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Involved in several processes, including autocrine signaling; response to ethanol; and response to lipopolysaccharide. Located in extracellular space. Biomarker of urinary bladder Cancer. Human ortholog(s) of this gene implicated in myocarditis. Orthologous to human S100A8 (S100 calcium binding protein A8). [provided by Alliance of Genome Resources, Apr 2022]

S100a8 Products (1)

mRNA Protein Name
NM_053822.2 NP_446274.2 protein S100-A8

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in autocrine signaling IGI
IGI: Inferred from genetic interaction
27312849 RGD
involved in chronic inflammatory response IEP
IEP: Inferred from expression pattern
8343166 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
17207109 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
17207109 RGD
involved in response to zinc ion IEP
IEP: Inferred from expression pattern
19111725 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
15221771 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein S100-A8

  • MRP-8

  • S100 calcium binding protein A8 (calgranulin A)

  • calgranulin-A

  • migration inhibitory factor-related protein 8

  • p8

Recombinant S100a8 Proteins

Cat. No. Product Name Accession Purity
HY-P71275 S100A8 Protein, Rat (His) P50115 (M1-E89) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-100442 Paquinimod Inhibitor 99.90% Phase 2

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-141537 ABR-238901 Inhibitor 98.92% Unkown
HY-100442S1 Paquinimod-d5-1 Inhibitor 98.19% Unkown
HY-RS16593 S100a8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12385 S100A8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-100442S Paquinimod-d5 Inhibitor / Unkown
HY-RS23027 S100a8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens S100a8 NCBI NCBI:6279